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Tau phosphorylation by glycogen synthase kinase 3β modulates enzyme acetylcholinesterase expression

In Alzheimer's disease (AD), the enzyme acetylcholinesterase (AChE) co‐localizes with hyperphosphorylated tau (P‐tau) within neurofibrillary tangles. Having demonstrated that AChE expression is increased in the transgenic mouse model of tau Tg‐VLW, here we examined whether modulating phosphoryl...

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Detalles Bibliográficos
Autores principales: Cortés‐Gómez, María‐Ángeles, Llorens‐Álvarez, Esther, Alom, Jordi, del Ser, Teodoro, Avila, Jesús, Sáez‐Valero, Javier, García‐Ayllón, María‐Salud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359467/
https://www.ncbi.nlm.nih.gov/pubmed/32955735
http://dx.doi.org/10.1111/jnc.15189