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The cGMP system in normal and degenerating mouse neuroretina: New proteins with cGMP interaction potential identified by a proteomics approach

The hereditary disease Retinitis pigmentosa results in severe vision loss due to photoreceptor degeneration by unclear mechanisms. In several disease models, the second messenger cGMP accumulates in the degenerating photoreceptors, where it may over‐activate specific cGMP‐interacting proteins, like...

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Detalles Bibliográficos
Autores principales: Rasmussen, Michel, Welinder, Charlotte, Schwede, Frank, Ekström, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359485/
https://www.ncbi.nlm.nih.gov/pubmed/33230839
http://dx.doi.org/10.1111/jnc.15251