Phosphorylation of NF-κBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target

BACKGROUND: Nuclear factor­κB (NF-κB) plays a vital role in hepatocellular carcinoma (HCC). β-arrestin1 (ARRB1) has been proved to enhance the activity of NF-κBp65, and our previous study indicated that ARRB1 promotes hepatocellular carcinogenesis and development of HCC. However, it remains unknown...

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Detalles Bibliográficos
Autores principales: Xu, Xuan, Lei, Yiming, Chen, Lingjun, Zhou, Haoxiong, Liu, Huiling, Jiang, Jie, Yang, Yidong, Wu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359590/
https://www.ncbi.nlm.nih.gov/pubmed/34380537
http://dx.doi.org/10.1186/s13046-021-02062-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359590/
https://www.ncbi.nlm.nih.gov/pubmed/34380537
http://dx.doi.org/10.1186/s13046-021-02062-x

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