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Proteomic landscape of Alzheimer’s Disease: novel insights into pathogenesis and biomarker discovery

Mass spectrometry-based proteomics empowers deep profiling of proteome and protein posttranslational modifications (PTMs) in Alzheimer’s disease (AD). Here we review the advances and limitations in historic and recent AD proteomic research. Complementary to genetic mapping, proteomic studies not onl...

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Detalles Bibliográficos
Autores principales: Bai, Bing, Vanderwall, David, Li, Yuxin, Wang, Xusheng, Poudel, Suresh, Wang, Hong, Dey, Kaushik Kumar, Chen, Ping-Chung, Yang, Ka, Peng, Junmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359598/
https://www.ncbi.nlm.nih.gov/pubmed/34384464
http://dx.doi.org/10.1186/s13024-021-00474-z