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Potent prophylactic and therapeutic efficacy of recombinant human ACE2-Fc against SARS-CoV-2 infection in vivo

The current COVID-19 pandemic, caused by SARS-CoV-2, poses a serious public health threat. Effective therapeutic and prophylactic treatments are urgently needed. Angiotensin-converting enzyme 2 (ACE2) is a functional receptor for SARS-CoV-2, which binds to the receptor binding domain (RBD) of SARS-C...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoyong, Zeng, Eric, Zhang, Lu, Wang, Weiming, Jin, Yingkang, Sun, Jiye, Huang, Shuxiang, Yin, Wenguang, Dai, Jun, Zhuang, Zhen, Chen, Zhao, Sun, Jing, Zhu, Airu, Li, Fang, Cao, Weitao, Li, Xiaobo, Shi, Yongxia, Gan, Mian, Zhang, Shengnan, Wei, Peilan, Huang, Jicheng, Zhong, Nanshan, Zhong, Guocai, Zhao, Jingxian, Wang, Yanqun, Shao, Weihui, Zhao, Jincun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359631/
https://www.ncbi.nlm.nih.gov/pubmed/34385423
http://dx.doi.org/10.1038/s41421-021-00302-0