Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects

AIMS: This study aims to develop and verify a physiologically based pharmacokinetic (PBPK) population model for the Chinese geriatric population in Simcyp. METHODS: Firstly, physiological information for the Chinese geriatric population was collected and later employed to develop the Chinese geriatr...

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Detalles Bibliográficos
Autores principales: Cui, Cheng, Valerie Sia, Jie En, Tu, Siqi, Li, Xiaobei, Dong, Zhongqi, Yu, Zhiheng, Yao, Xueting, Hatley, Oliver, Li, Haiyan, Liu, Dongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359847/
https://www.ncbi.nlm.nih.gov/pubmed/33068053
http://dx.doi.org/10.1111/bcp.14609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359847/
https://www.ncbi.nlm.nih.gov/pubmed/33068053
http://dx.doi.org/10.1111/bcp.14609

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