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Development of a physiologically based pharmacokinetic (PBPK) population model for Chinese elderly subjects
AIMS: This study aims to develop and verify a physiologically based pharmacokinetic (PBPK) population model for the Chinese geriatric population in Simcyp. METHODS: Firstly, physiological information for the Chinese geriatric population was collected and later employed to develop the Chinese geriatr...
Autores principales: | Cui, Cheng, Valerie Sia, Jie En, Tu, Siqi, Li, Xiaobei, Dong, Zhongqi, Yu, Zhiheng, Yao, Xueting, Hatley, Oliver, Li, Haiyan, Liu, Dongyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359847/ https://www.ncbi.nlm.nih.gov/pubmed/33068053 http://dx.doi.org/10.1111/bcp.14609 |
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