Neuromuscular junction instability and altered intracellular calcium handling as early determinants of force loss during unloading in humans

KEY POINTS: Few days of unloading are sufficient to induce a decline of skeletal muscle mass and function; notably, contractile force is lost at a faster rate than muscle mass. The reasons behind this disproportionate loss of muscle force are still poorly understood. We provide strong evidence of tw...

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Detalles Bibliográficos
Autores principales: Monti, Elena, Reggiani, Carlo, Franchi, Martino V., Toniolo, Luana, Sandri, Marco, Armani, Andrea, Zampieri, Sandra, Giacomello, Emiliana, Sarto, Fabio, Sirago, Giuseppe, Murgia, Marta, Nogara, Leonardo, Marcucci, Lorenzo, Ciciliot, Stefano, Šimunic, Boštjan, Pišot, Rado, Narici, Marco V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Muscle
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359852/
https://www.ncbi.nlm.nih.gov/pubmed/33881176
http://dx.doi.org/10.1113/JP281365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8359852/
https://www.ncbi.nlm.nih.gov/pubmed/33881176
http://dx.doi.org/10.1113/JP281365

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