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Serotonin 5‐HT7 receptors require cyclin‐dependent kinase 5 to rescue hippocampal synaptic plasticity in a mouse model of Fragile X Syndrome

Fragile X Syndrome is a genetic form of intellectual disability associated with autism, epilepsy and mood disorders. Electrophysiology studies in Fmr1 knockout (KO) mice, a murine model of Fragile X Syndrome, have demonstrated alterations of synaptic plasticity, with exaggerated long‐term depression...

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Detalles Bibliográficos
Autores principales: Costa, Lara, Tempio, Alessandra, Lacivita, Enza, Leopoldo, Marcello, Ciranna, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360017/
https://www.ncbi.nlm.nih.gov/pubmed/33949019
http://dx.doi.org/10.1111/ejn.15246