PAD4 takes charge during neutrophil activation: Impact of PAD4 mediated NET formation on immune‐mediated disease

Background: Peptidyl arginine deiminase 4 (PAD4) is an enzyme that converts arginine into citrulline. PAD4 is expressed in neutrophils that, when activated, can drive the formation of neutrophil extracellular traps (NETs). Uncontrolled activation of PAD4 and subsequent citrullination of proteins is...

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Detalles Bibliográficos
Autores principales: Liu, Xiaosong, Arfman, Tom, Wichapong, Kanin, Reutelingsperger, Chris P. M., Voorberg, Jan, Nicolaes, Gerry A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360066/
https://www.ncbi.nlm.nih.gov/pubmed/33773016
http://dx.doi.org/10.1111/jth.15313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360066/
https://www.ncbi.nlm.nih.gov/pubmed/33773016
http://dx.doi.org/10.1111/jth.15313

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