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FVIII inhibitors display FV‐neutralizing activity in the prothrombin time assay
BACKGROUND: The coagulation factors (F)V and VIII are homologous proteins that support hemostasis through their regulation of FX activity. Hemophilia A (HA) patients have reduced FVIII activity and a prolonged bleeding time that is corrected through the administration of exogenous FVIII. Around one‐...
Autores principales: | Arsiccio, Andrea, Beavis, James, Raut, Sanj, Coxon, Carmen H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360109/ https://www.ncbi.nlm.nih.gov/pubmed/33914406 http://dx.doi.org/10.1111/jth.15355 |
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