The structure of POMGNT2 provides new insights into the mechanism to determine the functional O‐mannosylation site on α‐dystroglycan

Defects in the O‐mannosyl glycan of α‐dystroglycan (α‐DG) are associated with α‐dystroglycanopathy, a group of congenital muscular dystrophies. While α‐DG has many O‐mannosylation sites, only the specific positions can be modified with the functional O‐mannosyl glycan, namely, core M3‐type glycan. P...

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Detalles Bibliográficos
Autores principales: Imae, Rieko, Kuwabara, Naoyuki, Manya, Hiroshi, Tanaka, Tomohiro, Tsuyuguchi, Masato, Mizuno, Mamoru, Endo, Tamao, Kato, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360118/
https://www.ncbi.nlm.nih.gov/pubmed/33893702
http://dx.doi.org/10.1111/gtc.12853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360118/
https://www.ncbi.nlm.nih.gov/pubmed/33893702
http://dx.doi.org/10.1111/gtc.12853

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