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The structure of POMGNT2 provides new insights into the mechanism to determine the functional O‐mannosylation site on α‐dystroglycan
Defects in the O‐mannosyl glycan of α‐dystroglycan (α‐DG) are associated with α‐dystroglycanopathy, a group of congenital muscular dystrophies. While α‐DG has many O‐mannosylation sites, only the specific positions can be modified with the functional O‐mannosyl glycan, namely, core M3‐type glycan. P...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360118/ https://www.ncbi.nlm.nih.gov/pubmed/33893702 http://dx.doi.org/10.1111/gtc.12853 |