Development of NanoBRET‐Binding Assays for FKBP‐Ligand Profiling in Living Cells

FK506‐binding proteins (FKBPs) are promising targets for a variety of disorders and infectious diseases. High FKBP occupancy is thought to be necessary for ligands to effectively compete with the endogenous intracellular functions of FKBPs. Here, we report the development of NanoBRET assays for the...

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Detalles Bibliográficos
Autores principales: Gnatzy, Monika T., Geiger, Thomas M., Kuehn, Angela, Gutfreund, Niklas, Walz, Michael, Kolos, Jürgen M., Hausch, Felix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360185/
https://www.ncbi.nlm.nih.gov/pubmed/33887102
http://dx.doi.org/10.1002/cbic.202100113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360185/
https://www.ncbi.nlm.nih.gov/pubmed/33887102
http://dx.doi.org/10.1002/cbic.202100113

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