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Impaired Very‐Low‐Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia

Prevention of hypertriglyceridemia is one of the biomedical targets in Glycogen Storage Disease type Ia (GSD Ia) patients, yet it is unclear how hypoglycemia links to plasma triglyceride (TG) levels. We analyzed whole‐body TG metabolism in normoglycemic (fed) and hypoglycemic (fasted) hepatocyte‐spe...

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Detalles Bibliográficos
Autores principales: Hoogerland, Joanne A., Peeks, Fabian, Hijmans, Brenda S., Wolters, Justina C., Kooijman, Sander, Bos, Trijnie, Bleeker, Aycha, van Dijk, Theo H., Wolters, Henk, Gerding, Albert, van Eunen, Karen, Havinga, Rick, Pronk, Amanda C. M., Rensen, Patrick C. N., Mithieux, Gilles, Rajas, Fabienne, Kuipers, Folkert, Reijngoud, Dirk‐Jan, Derks, Terry G. J., Oosterveer, Maaike H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360207/
https://www.ncbi.nlm.nih.gov/pubmed/33739445
http://dx.doi.org/10.1002/jimd.12380