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Effect of crista morphology on mitochondrial ATP output: A computational study

Folding of the mitochondrial inner membrane (IM) into cristae greatly increases the ATP-generating surface area, S(IM), per unit volume but also creates diffusional bottlenecks that could limit reaction rates inside mitochondria. This study explores possible effects of inner membrane folding on mito...

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Detalles Bibliográficos
Autores principales: Afzal, Nasrin, Lederer, W. Jonathan, Jafri, M. Saleet, Mannella, Carmen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360328/
https://www.ncbi.nlm.nih.gov/pubmed/34396153
http://dx.doi.org/10.1016/j.crphys.2021.03.005