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Effect of crista morphology on mitochondrial ATP output: A computational study
Folding of the mitochondrial inner membrane (IM) into cristae greatly increases the ATP-generating surface area, S(IM), per unit volume but also creates diffusional bottlenecks that could limit reaction rates inside mitochondria. This study explores possible effects of inner membrane folding on mito...
Autores principales: | Afzal, Nasrin, Lederer, W. Jonathan, Jafri, M. Saleet, Mannella, Carmen A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360328/ https://www.ncbi.nlm.nih.gov/pubmed/34396153 http://dx.doi.org/10.1016/j.crphys.2021.03.005 |
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