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Matrigel is required for efficient differentiation of isolated, stem cell-derived otic vesicles into inner ear organoids

Inner ear organoids derived from pluripotent stem cells could be a useful model system to study development, disease, and regeneration. However, there is considerable heterogeneity in the size, morphology, and efficiency of organoid production using standard protocols. Greater control of the culture...

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Detalles Bibliográficos
Autores principales: Hocevar, Sarah Emily, Liu, Liqian, Duncan, Robert Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360351/
https://www.ncbi.nlm.nih.gov/pubmed/33773390
http://dx.doi.org/10.1016/j.scr.2021.102295