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Matrigel is required for efficient differentiation of isolated, stem cell-derived otic vesicles into inner ear organoids
Inner ear organoids derived from pluripotent stem cells could be a useful model system to study development, disease, and regeneration. However, there is considerable heterogeneity in the size, morphology, and efficiency of organoid production using standard protocols. Greater control of the culture...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360351/ https://www.ncbi.nlm.nih.gov/pubmed/33773390 http://dx.doi.org/10.1016/j.scr.2021.102295 |