Norcycloartocarpin targets Akt and suppresses Akt-dependent survival and epithelial-mesenchymal transition in lung cancer cells

In searching for novel targeted therapeutic agents for lung cancer treatment, norcycloartocarpin from Artocarpus gomezianus was reported in this study to promisingly interacted with Akt and exerted the apoptosis induction and epithelial-to-mesenchymal transition suppression. Selective cytotoxic prof...

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Detalles Bibliográficos
Autores principales: Nonpanya, Nongyao, Sanookpan, Kittipong, Joyjamras, Keerati, Wichadakul, Duangdao, Sritularak, Boonchoo, Chaotham, Chatchai, Chanvorachote, Pithi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360371/
https://www.ncbi.nlm.nih.gov/pubmed/34383763
http://dx.doi.org/10.1371/journal.pone.0254929

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360371/
https://www.ncbi.nlm.nih.gov/pubmed/34383763
http://dx.doi.org/10.1371/journal.pone.0254929

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