Cargando…

Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription

Beta- and gammaherpesviruses late transcription factors (LTFs) target viral promoters containing a TATT sequence to drive transcription after viral DNA replication has begun. Human cytomegalovirus (HCMV), a betaherpesvirus, uses the UL87 LTF to bind both TATT and host RNA polymerase II (Pol II), whe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Ming, Hu, Qiaolin, Collins, Geoffrey, Parida, Mrutyunjaya, Ball, Christopher B., Price, David H., Meier, Jeffery L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360532/
https://www.ncbi.nlm.nih.gov/pubmed/34339482
http://dx.doi.org/10.1371/journal.ppat.1009796