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Cytomegalovirus late transcription factor target sequence diversity orchestrates viral early to late transcription
Beta- and gammaherpesviruses late transcription factors (LTFs) target viral promoters containing a TATT sequence to drive transcription after viral DNA replication has begun. Human cytomegalovirus (HCMV), a betaherpesvirus, uses the UL87 LTF to bind both TATT and host RNA polymerase II (Pol II), whe...
Autores principales: | Li, Ming, Hu, Qiaolin, Collins, Geoffrey, Parida, Mrutyunjaya, Ball, Christopher B., Price, David H., Meier, Jeffery L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360532/ https://www.ncbi.nlm.nih.gov/pubmed/34339482 http://dx.doi.org/10.1371/journal.ppat.1009796 |
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