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Association of fibroblast growth factor 10 with the fibrotic and inflammatory pathogenesis of Graves’ orbitopathy

PURPOSE: The role of fibroblast growth factor (FGF) in orbital fibroblasts (OFs) is rarely known. In this study, we investigated the effect of FGF10 on fibrosis and the inflammation mechanism of Graves′ orbitopathy (GO). METHODS: Orbital tissue from GO (n = 15) and non-GO (n = 15) was obtained for t...

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Detalles Bibliográficos
Autores principales: Jang, Sun Young, Choi, Soo Hyun, Kikkawa, Don, Lee, Eun Jig, Yoon, Jin Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360584/
https://www.ncbi.nlm.nih.gov/pubmed/34383782
http://dx.doi.org/10.1371/journal.pone.0255344