Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses

Viruses have evolved means to manipulate the host’s ubiquitin-proteasome system, in order to down-regulate antiviral host factors. The Vpx/Vpr family of lentiviral accessory proteins usurp the substrate receptor DCAF1 of host Cullin4-RING ligases (CRL4), a family of modular ubiquitin ligases involve...

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Detalles Bibliográficos
Autores principales: Banchenko, Sofia, Krupp, Ferdinand, Gotthold, Christine, Bürger, Jörg, Graziadei, Andrea, O’Reilly, Francis J., Sinn, Ludwig, Ruda, Olga, Rappsilber, Juri, Spahn, Christian M. T., Mielke, Thorsten, Taylor, Ian A., Schwefel, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360603/
https://www.ncbi.nlm.nih.gov/pubmed/34339457
http://dx.doi.org/10.1371/journal.ppat.1009775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360603/
https://www.ncbi.nlm.nih.gov/pubmed/34339457
http://dx.doi.org/10.1371/journal.ppat.1009775

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