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Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses
Viruses have evolved means to manipulate the host’s ubiquitin-proteasome system, in order to down-regulate antiviral host factors. The Vpx/Vpr family of lentiviral accessory proteins usurp the substrate receptor DCAF1 of host Cullin4-RING ligases (CRL4), a family of modular ubiquitin ligases involve...
Autores principales: | Banchenko, Sofia, Krupp, Ferdinand, Gotthold, Christine, Bürger, Jörg, Graziadei, Andrea, O’Reilly, Francis J., Sinn, Ludwig, Ruda, Olga, Rappsilber, Juri, Spahn, Christian M. T., Mielke, Thorsten, Taylor, Ian A., Schwefel, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360603/ https://www.ncbi.nlm.nih.gov/pubmed/34339457 http://dx.doi.org/10.1371/journal.ppat.1009775 |
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