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Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial–mesenchymal transition in proliferative vitreoretinopathy

The purpose of this study was to assess whether microRNA (miR)-1285 can suppress the epithelial–mesenchymal transition (EMT) in retinal pigment epithelial cells. Expression of miR-1285 was evaluated using quantitative real-time polymerase chain reaction (RT-qPCR). The features of EMT were assessed u...

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Detalles Bibliográficos
Autores principales: Pao, Shu-I, Lin, Le-Tien, Chen, Yi-Hao, Chen, Ching-Long, Chen, Jiann-Torng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360606/
https://www.ncbi.nlm.nih.gov/pubmed/34383767
http://dx.doi.org/10.1371/journal.pone.0254873