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Effects of Tocilizumab Therapy on Circulating B Cells and T Helper Cells in Patients With Neuromyelitis Optica Spectrum Disorder

Tocilizumab, a humanized anti-IL-6 receptor monoclonal antibody, showed its therapeutic efficacy on neuromyelitis optica spectrum disorder (NMOSD). To assess the immunological effects of this drug on B cells, follicular T helper (Tfh) cells, and peripheral T helper (Tph) cells in patients with NMOSD...

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Detalles Bibliográficos
Autores principales: Liu, Ye, Zhang, Huiming, Zhang, Tian-Xiang, Yuan, Meng, Du, Chen, Zeng, Pei, Huang, Zhenning, Jia, Dongmei, Yang, Guili, Shi, Fu-Dong, Zhang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360623/
https://www.ncbi.nlm.nih.gov/pubmed/34394101
http://dx.doi.org/10.3389/fimmu.2021.703931