Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1‐mediated MAPK signaling

BACKGROUND: Colorectal cancer (CRC) is one of the most malignant tumors with high incidence, yet its molecular mechanism is not fully understood, hindering the development of targeted therapy. Metabolic abnormalities are a hallmark of cancer. Targeting dysregulated metabolic features has become an i...

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Detalles Bibliográficos
Autores principales: He, Luwei, Li, Huaguang, Pan, Chenyu, Hua, Yutong, Peng, Jiayin, Zhou, Zhaocai, Zhao, Yun, Lin, Moubin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360641/
https://www.ncbi.nlm.nih.gov/pubmed/34268906
http://dx.doi.org/10.1002/cac2.12187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360641/
https://www.ncbi.nlm.nih.gov/pubmed/34268906
http://dx.doi.org/10.1002/cac2.12187

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