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CXCL10/CXCR3 signaling contributes to an inflammatory microenvironment and its blockade enhances progression of murine pancreatic precancerous lesions

The development of pancreatic cancer requires recruitment and activation of different macrophage populations. However, little is known about how macrophages are attracted to the pancreas after injury or an oncogenic event, and how they crosstalk with lesion cells or other cells of the lesion microen...

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Detalles Bibliográficos
Autores principales: Pandey, Veethika, Fleming-Martinez, Alicia, Bastea, Ligia, Doeppler, Heike R, Eisenhauer, Jillian, Le, Tam, Edenfield, Brandy, Storz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360647/
https://www.ncbi.nlm.nih.gov/pubmed/34328416
http://dx.doi.org/10.7554/eLife.60646