Loss of centromeric RNA activates the spindle assembly checkpoint in mammalian female meiosis I

The repetitive sequences of DNA centromeric regions form the structural basis for kinetochore assembly. Recently they were found to be transcriptionally active in mitosis, with their RNAs providing noncoding functions. Here we explore the role, in mouse oocytes, of transcripts generated from within...

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Detalles Bibliográficos
Autores principales: Wu, Tianyu, Lane, Simon I.R., Morgan, Stephanie L., Tang, Feng, Jones, Keith T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360762/
https://www.ncbi.nlm.nih.gov/pubmed/34379093
http://dx.doi.org/10.1083/jcb.202011153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360762/
https://www.ncbi.nlm.nih.gov/pubmed/34379093
http://dx.doi.org/10.1083/jcb.202011153

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