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Loss of centromeric RNA activates the spindle assembly checkpoint in mammalian female meiosis I
The repetitive sequences of DNA centromeric regions form the structural basis for kinetochore assembly. Recently they were found to be transcriptionally active in mitosis, with their RNAs providing noncoding functions. Here we explore the role, in mouse oocytes, of transcripts generated from within...
Autores principales: | Wu, Tianyu, Lane, Simon I.R., Morgan, Stephanie L., Tang, Feng, Jones, Keith T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360762/ https://www.ncbi.nlm.nih.gov/pubmed/34379093 http://dx.doi.org/10.1083/jcb.202011153 |
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