Regulatory T cells promote glioma cell stemness through TGF-β–NF-κB–IL6–STAT3 signaling

Glioma stem cells (GSCs) contribute to the malignant growth of glioma, but little is known about the interaction between GSCs and tumor microenvironment. Here, we found that intense infiltration of regulatory T cells (Tregs) facilitated the qualities of GSCs through TGF-β secretion that helped coord...

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Detalles Bibliográficos
Autores principales: Liu, Shasha, Zhang, Chaoqi, Wang, Boqiao, Zhang, Huanyu, Qin, Guohui, Li, Congcong, Cao, Ling, Gao, Qun, Ping, Yu, Zhang, Kai, Lian, Jingyao, Zhao, Qitai, Wang, Dan, Zhang, Zhen, Zhao, Xuan, Yang, Li, Huang, Lan, Yang, Bo, Zhang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360896/
https://www.ncbi.nlm.nih.gov/pubmed/33576874
http://dx.doi.org/10.1007/s00262-021-02872-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360896/
https://www.ncbi.nlm.nih.gov/pubmed/33576874
http://dx.doi.org/10.1007/s00262-021-02872-0

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