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Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients

The spleen, a secondary lymphoid tissue (SLT), has an important role in generation of adaptive immune responses. Although splenectomy remains a common procedure, recent studies reported poor prognosis and increased risk of haematological malignancies in asplenic patients. The high baseline trafficki...

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Detalles Bibliográficos
Autores principales: Kmieciak, Aleksandra E., Brown, Liam V., Coles, Mark C., Wagg, Jonathan, Phipps, Alex, Gaffney, Eamonn A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360980/
https://www.ncbi.nlm.nih.gov/pubmed/34385480
http://dx.doi.org/10.1038/s41598-021-95225-x