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Predicted limited redistribution of T cells to secondary lymphoid tissue correlates with increased risk of haematological malignancies in asplenic patients
The spleen, a secondary lymphoid tissue (SLT), has an important role in generation of adaptive immune responses. Although splenectomy remains a common procedure, recent studies reported poor prognosis and increased risk of haematological malignancies in asplenic patients. The high baseline trafficki...
Autores principales: | Kmieciak, Aleksandra E., Brown, Liam V., Coles, Mark C., Wagg, Jonathan, Phipps, Alex, Gaffney, Eamonn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360980/ https://www.ncbi.nlm.nih.gov/pubmed/34385480 http://dx.doi.org/10.1038/s41598-021-95225-x |
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