Interferon lambda 4 impairs hepatitis C viral antigen presentation and attenuates T cell responses

Genetic variants of the interferon lambda (IFNL) gene locus are strongly associated with spontaneous and IFN treatment-induced clearance of hepatitis C virus (HCV) infections. Individuals with the ancestral IFNL4-dG allele are not able to clear HCV in the acute phase and have more than a 90% probabi...

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Detalles Bibliográficos
Autores principales: Chen, Qian, Coto-Llerena, Mairene, Suslov, Aleksei, Teixeira, Raphael Dias, Fofana, Isabel, Nuciforo, Sandro, Hofmann, Maike, Thimme, Robert, Hensel, Nina, Lohmann, Volker, Ng, Charlotte K. Y., Rosenberger, George, Wieland, Stefan, Heim, Markus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360984/
https://www.ncbi.nlm.nih.gov/pubmed/34385466
http://dx.doi.org/10.1038/s41467-021-25218-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360984/
https://www.ncbi.nlm.nih.gov/pubmed/34385466
http://dx.doi.org/10.1038/s41467-021-25218-x

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