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Expression of a human cDNA in moss results in spliced mRNAs and fragmentary protein isoforms
Production of biopharmaceuticals relies on the expression of mammalian cDNAs in host organisms. Here we show that the expression of a human cDNA in the moss Physcomitrium patens generates the expected full-length and four additional transcripts due to unexpected splicing. This mRNA splicing results...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361020/ https://www.ncbi.nlm.nih.gov/pubmed/34385580 http://dx.doi.org/10.1038/s42003-021-02486-3 |