Topological isolation of developmental regulators in mammalian genomes

Precise control of mammalian gene expression is facilitated through epigenetic mechanisms and nuclear organization. In particular, insulated chromosome structures are important for regulatory control, but the phenotypic consequences of their boundary disruption on developmental processes are complex...

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Detalles Bibliográficos
Autores principales: Wu, Hua-Jun, Landshammer, Alexandro, Stamenova, Elena K., Bolondi, Adriano, Kretzmer, Helene, Meissner, Alexander, Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361032/
https://www.ncbi.nlm.nih.gov/pubmed/34385432
http://dx.doi.org/10.1038/s41467-021-24951-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361032/
https://www.ncbi.nlm.nih.gov/pubmed/34385432
http://dx.doi.org/10.1038/s41467-021-24951-7

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