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Estimating the predictive power of silent mutations on cancer classification and prognosis

In recent years it has been shown that silent mutations, in and out of the coding region, can affect gene expression and may be related to tumorigenesis and cancer cell fitness. However, the predictive ability of these mutations for cancer type diagnosis and prognosis has not been evaluated yet. In...

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Detalles Bibliográficos
Autores principales: Gutman, Tal, Goren, Guy, Efroni, Omri, Tuller, Tamir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361094/
https://www.ncbi.nlm.nih.gov/pubmed/34385450
http://dx.doi.org/10.1038/s41525-021-00229-1