Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters

α-ketoglutarate (KG), also referred to as 2-oxoglutarate, is a key intermediate of cellular metabolism with pleiotropic functions. Cell-permeable esterified analogs are widely used to study how KG fuels bioenergetic and amino acid metabolism and DNA, RNA, and protein hydroxylation reactions, as cell...

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Detalles Bibliográficos
Autores principales: Parker, Seth J., Encarnación-Rosado, Joel, Hollinshead, Kate E. R., Hollinshead, David M., Ash, Leonard J., Rossi, Juan A. K., Lin, Elaine Y., Sohn, Albert S. W., Philips, Mark R., Jones, Drew R., Kimmelman, Alec C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361106/
https://www.ncbi.nlm.nih.gov/pubmed/34385458
http://dx.doi.org/10.1038/s41467-021-25228-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361106/
https://www.ncbi.nlm.nih.gov/pubmed/34385458
http://dx.doi.org/10.1038/s41467-021-25228-9

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