Spontaneous hydrolysis and spurious metabolic properties of α-ketoglutarate esters

α-ketoglutarate (KG), also referred to as 2-oxoglutarate, is a key intermediate of cellular metabolism with pleiotropic functions. Cell-permeable esterified analogs are widely used to study how KG fuels bioenergetic and amino acid metabolism and DNA, RNA, and protein hydroxylation reactions, as cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Parker, Seth J., Encarnación-Rosado, Joel, Hollinshead, Kate E. R., Hollinshead, David M., Ash, Leonard J., Rossi, Juan A. K., Lin, Elaine Y., Sohn, Albert S. W., Philips, Mark R., Jones, Drew R., Kimmelman, Alec C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361106/
https://www.ncbi.nlm.nih.gov/pubmed/34385458
http://dx.doi.org/10.1038/s41467-021-25228-9

Ejemplares similares

Ejemplares similares