Cargando…

Organocatalytic enantioselective dearomatization of thiophenes by 1,10-conjugate addition of indole imine methides

Catalytic asymmetric dearomatization (CADA) is a powerful tool for the rapid construction of diverse chiral cyclic molecules from cheap and easily available arenes. This work reports an organocatalytic enantioselective dearomatization of substituted thiophenes in the context of a rare remote asymmet...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Xingguang, Duan, Meng, Yu, Peiyuan, Houk, K. N., Sun, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361129/
https://www.ncbi.nlm.nih.gov/pubmed/34385441
http://dx.doi.org/10.1038/s41467-021-25165-7