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GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans

Chronically elevated intraocular pressure (IOP) is the major risk factor of primary open-angle glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM), which controls the outflow of aqueous humor (AqH) from the anterior chamber, is the major cause of elevated IOP. Here, w...

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Detalles Bibliográficos
Autores principales: Nair, K. Saidas, Srivastava, Chitrangda, Brown, Robert V., Koli, Swanand, Choquet, Hélène, Kang, Hong Soon, Kuo, Yien-Ming, Grimm, Sara A., Sutherland, Caleb, Badea, Alexandra, Johnson, G. Allan, Zhao, Yin, Yin, Jie, Okamoto, Kyoko, Clark, Graham, Borrás, Terete, Zode, Gulab, Kizhatil, Krishnakumar, Chakrabarti, Subhabrata, John, Simon W. M., Jorgenson, Eric, Jetten, Anton M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361148/
https://www.ncbi.nlm.nih.gov/pubmed/34385434
http://dx.doi.org/10.1038/s41467-021-25181-7