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GLIS1 regulates trabecular meshwork function and intraocular pressure and is associated with glaucoma in humans
Chronically elevated intraocular pressure (IOP) is the major risk factor of primary open-angle glaucoma, a leading cause of blindness. Dysfunction of the trabecular meshwork (TM), which controls the outflow of aqueous humor (AqH) from the anterior chamber, is the major cause of elevated IOP. Here, w...
Autores principales: | Nair, K. Saidas, Srivastava, Chitrangda, Brown, Robert V., Koli, Swanand, Choquet, Hélène, Kang, Hong Soon, Kuo, Yien-Ming, Grimm, Sara A., Sutherland, Caleb, Badea, Alexandra, Johnson, G. Allan, Zhao, Yin, Yin, Jie, Okamoto, Kyoko, Clark, Graham, Borrás, Terete, Zode, Gulab, Kizhatil, Krishnakumar, Chakrabarti, Subhabrata, John, Simon W. M., Jorgenson, Eric, Jetten, Anton M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361148/ https://www.ncbi.nlm.nih.gov/pubmed/34385434 http://dx.doi.org/10.1038/s41467-021-25181-7 |
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