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Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation
Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability while the d...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361156/ https://www.ncbi.nlm.nih.gov/pubmed/34385547 http://dx.doi.org/10.1038/s41598-021-95941-4 |