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Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation

Api5, is a known anti-apoptotic and nuclear protein that is responsible for inhibiting cell death in serum-starved conditions. The only known post-translational modification of Api5 is acetylation at lysine 251 (K251). K251 acetylation of Api5 is responsible for maintaining its stability while the d...

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Detalles Bibliográficos
Autores principales: Sharma, Virender Kumar, Lahiri, Mayurika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361156/
https://www.ncbi.nlm.nih.gov/pubmed/34385547
http://dx.doi.org/10.1038/s41598-021-95941-4