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Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis

Neuroendocrine prostate cancer is an aggressive variant of prostate cancer that may arise de novo or develop from pre-existing prostate adenocarcinoma as a mechanism of treatment resistance. The combined loss of tumor suppressors RB1, TP53, and PTEN are frequent in NEPC but also present in a subset...

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Detalles Bibliográficos
Autores principales: Conteduca, Vincenza, Ku, Sheng-Yu, Fernandez, Luisa, Dago-Rodriquez, Angel, Lee, Jerry, Jendrisak, Adam, Slade, Megan, Gilbertson, Cole, Manohar, Jyothi, Sigouros, Michael, Wang, Yipeng, Dittamore, Ryan, Wenstrup, Rick, Mosquera, Juan Miguel, Schonhoft, Joseph D., Beltran, Himisha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361159/
https://www.ncbi.nlm.nih.gov/pubmed/34385567
http://dx.doi.org/10.1038/s41698-021-00211-1