Constitutive BAK/MCL1 complexes predict paclitaxel and S63845 sensitivity of ovarian cancer

We previously found that preformed complexes of BAK with antiapoptotic BCL2 proteins predict BH3 mimetic sensitivities in lymphohematopoietic cells. These complexes have not previously been examined in solid tumors or in the context of conventional anticancer drugs. Here we show the relative amount...

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Detalles Bibliográficos
Autores principales: Liu, Dongyan, Hou, Xiaonan, Wu, Wangyu, Zanfagnin, Valentina, Li, Yunjian, Correia, Cristina, Zhao, Zhiyang, Zhao, Chenggang, Liu, Zhirong, Zhang, Tao, Fang, Zhiyou, Wang, Hongzhi, Xu, Chao, Weroha, Saravut J., Kaufmann, Scott H., Dai, Haiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361168/
https://www.ncbi.nlm.nih.gov/pubmed/34385422
http://dx.doi.org/10.1038/s41419-021-04073-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361168/
https://www.ncbi.nlm.nih.gov/pubmed/34385422
http://dx.doi.org/10.1038/s41419-021-04073-0

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