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Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions
The Tweety homologs (TTYHs) are members of a conserved family of eukaryotic membrane proteins that are abundant in the brain. The three human paralogs were assigned to function as anion channels that are either activated by Ca(2+) or cell swelling. To uncover their unknown architecture and its relat...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361169/ https://www.ncbi.nlm.nih.gov/pubmed/34385445 http://dx.doi.org/10.1038/s41467-021-25106-4 |