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Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4

Regulation of gene expression involves a complex and dynamic dialogue between transcription factors, chromatin remodelling and modification complexes and the basal transcription machinery. To address the function of the Taf4 subunit of general transcription factor TFIID in the regulation of insulin...

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Detalles Bibliográficos
Autores principales: Kleiber, Thomas, Davidson, Guillaume, Mengus, Gabrielle, Martianov, Igor, Davidson, Irwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361202/
https://www.ncbi.nlm.nih.gov/pubmed/34385420
http://dx.doi.org/10.1038/s41419-021-04067-y