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Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4
Regulation of gene expression involves a complex and dynamic dialogue between transcription factors, chromatin remodelling and modification complexes and the basal transcription machinery. To address the function of the Taf4 subunit of general transcription factor TFIID in the regulation of insulin...
Autores principales: | Kleiber, Thomas, Davidson, Guillaume, Mengus, Gabrielle, Martianov, Igor, Davidson, Irwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361202/ https://www.ncbi.nlm.nih.gov/pubmed/34385420 http://dx.doi.org/10.1038/s41419-021-04067-y |
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