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Hexanol biosynthesis from syngas by Clostridium carboxidivorans P7 – product toxicity, temperature dependence and in situ extraction

Clostridium carboxidivorans converts syngas into industrial alcohols like hexanol, but titers may be limited by product toxicity. Investigation of IC(50) at 30 °C (17.5 mM) and 37 °C (11.8 mM) revealed increased hexanol tolerance at lower temperatures. To avoid product toxicity, oleyl alcohol was ad...

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Detalles Bibliográficos
Autores principales: Kottenhahn, Patrick, Philipps, Gabriele, Jennewein, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8361263/
https://www.ncbi.nlm.nih.gov/pubmed/34409191
http://dx.doi.org/10.1016/j.heliyon.2021.e07732